Declining Transition Rate in Ultra High Risk (Prodromal) Services: Dilution or Reduction of Risk?
نویسندگان
چکیده
منابع مشابه
Declining transition rate in ultra high risk (prodromal) services: dilution or reduction of risk?
There is growing interest in the prodromal stage of psychotic disorders, with many services now providing care for these "ultra high risk" (UHR) individuals. However, a reduction in the rate of transition to psychosis has been suspected over the last few years. This has implications for the use of interventions in this population and for the validity of research findings. This study examined th...
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Background Whilst robust preclinical and postmortem evidence suggests that altered GABAergic function is central to the development of psychosis, little is known about whether it is altered in subjects at ultra-high risk of psychosis, or its relationship to prodromal symptoms. Methods Twenty-one antipsychotic naïve ultra-high risk individuals and 20 healthy volunteers underwent proton magneti...
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OBJECTIVE Despite social environmental factors such as deprivation, urbanicity, migration and adversity being established risk factors for psychotic disorders, there is a paucity of knowledge on the influence of social environmental risk factors in the UHR population. Firstly, we aimed to investigate the association between social deprivation and risk of transition and secondly, we aimed to inv...
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ژورنال
عنوان ژورنال: Schizophrenia Bulletin
سال: 2007
ISSN: 0586-7614,1745-1701
DOI: 10.1093/schbul/sbm015